Alex de Mendoza
I did my PhD at the University of Barcelona (Spain) working on comparative genomics of unicellular relatives of animals with Prof. Iñaki Ruiz-Trillo. Then I trained as a postdoc in the laboratory of Prof. Ryan Lister at The University of Western Australia, working on comparative epigenomics of various organisms, from dinoflagellates to humans. From January 2020 I became a Lecturer and I run my own group at Queen Mary University of London, focusing on the evolution of epigenomes, transposable elements and everything in between.
I graduated with a Masters from the University of Sheffield in 2017, before moving to California to continue my studies with Joanne Chory at the Salk Institute for Biological Studies where I studied macromolecule synthesis and regulation in plants. My interest in evolution then took me to Columbia University to work with Professor Peter Andolfatto and Professor Molly Przeworski before beginning my PhD at Queen Mary University of London. Here I am studying the evolution of DNA methylation in unicellular eukaryotes.
During my PhD at the Institute of Cytology and Genetics SB RAS (Russian Federation), I studied microRNAs of parasitic flatworms using molecular and bioinformatics techniques under Dr Viatcheslav Mordvinov supervision. During my postdoc in the lab of Mary O’Connell at the University of Nottingham, I had a project on large-scale detection of selective pressure variation and gene birth and death analyses in a wide variety of vertebrates. My research interests are microRNAs, epigenetics, parasitology and evolution.
For my undergraduate project, I studied damage control in yeast with Professor Andrés Clemente Blanco at the University of Salamanca (Spain). Later, I did my Masters at Autonomous University of Barcelona (Spain), where I worked on stress response in unicellular relatives of animals with Professor Iñaki Ruíz-Trillo. Now, following my interests in genetics and evolution I find myself doing a PhD studying host gene capture by transposable elements and adenine methylation in unicellular eukaryotes.
I did my PhD study with Drs. Ten-Tsao Wong and Yonathan Zohar at Institute of Marine and Environmental Technology, University of Maryland Baltimore County, USA.. My research there focused on developing technologies to disrupt primordial germ cell development to produce reproductively sterile animals (zebrafish, salmonid, oyster) for aquaculture and I also studied the change of pituitary in sterile rainbow trout by single-cell RNA sequencing. My current research aims to understand the role of DNA methylation in the model invertebrate species starlet sea anemone Nematostella vectensis.
LIDo-DTP PhD student
My integrated Masters program at UCL in generalist biology gave me an appreciation for evolution and genetics. This degree included a Bachelor's project on the evolution of malaria, under Prof. Francois Balloux. I then conducted my Master's on a citizen science project dedicated to sampling the wasp diversity of the UK, with Prof. Seirian Sumner. Now, as a LIDo DTP student, I am researching evolutionary epigenomics, focusing on epigenomic engineering approaches in stem cells to understand the evolution of DNA methylation patterns.
Tahmina Omarzade - QMUL BSc in Medical Genetics last year project 2022-2023.
Deetya Patel - QMUL BSc in Medical Genetics last year project 2021-2023.
Yasemin Bridges - QMUL MSc in Bioinformatics project 2021-2022.
Parnia Babaei - QMUL BSc in Medical Genetics last year project 2021-2022.
Matous Elphick - Undergraduate summer research student, 2020.
Many of our projects are done in close collaboration with other laboratories, both at QMUL and elsewhere. Here we list some of the ongoing collaborators:
Martin-Duran Lab, QMUL.
Bogdanovic Lab, Garvan Institute of Medical Research, Australia.
Lister Lab, UWA, Australia.
Ferdinand Marlétaz Lab, University College London.
Genomic EvoDevo Lab, Hiroshima Prefectural University, Japan.
MulticellGenome Lab, Institute of Evolutionary Biology, Spain.
Florian Maumus, INRA, France.
Omaya Dudin Lab, École Polytechnique Fédérale de Lausanne, Switzerland.